

thermocellum can utilize lignocellulose waste and generate ethanol, thus making it a possible candidate for use in production of ethanol fuel. Bacillus amyloliquefaciens is the source of a natural antibiotic protein barnase (a ribonuclease), alpha amylase used in starch hydrolysis, the protease subtilisin used with detergents, and the BamH1 restriction enzyme used in DNA research.Many Bacillus species are able to secrete large quantities of enzymes. Non-pathogenic species of corynebacterium are used in industrial production of amino acids, nucleotides, bioconversion of steroids, degradation of hydrocarbons, cheese ageing, production of enzymes etc. They are also a necessary ingredient in producing Emmentaler (Swiss) cheese. Many streptococcal species are nonpathogenic, and form part of the commensal human microbiome of the mouth, skin, intestine, and upper respiratory tract.

These drugs are not likely to work on gram-negative bacteria. Greater resistance of gram-negative bacteria also applies to a newly discovered class of antibiotics that was announced in early 2015 after a decades-long drought in new antibiotics. They have a lot of tricks up their sleeves for developing resistance to antibiotics, so they’re a group of agents that can quickly become resistant, can pose major challenges to resistance.Īnd what we’ve seen over the past decade is these Gram-negative agents becoming very rapidly more and more resistant to all of the agents that we have available to treat them. These are bacteria that have historically done a very good job of very quickly developing resistance to antibiotics. We’re talking about agents with names like Acinetobacter, Pseudomonas, E. They also develop resistance sooner:Ī lot of Gram-negative bacteria, they come out of the box, if you will, resistant to a number of important antibiotics that we might use to treat them. Gram-negative bacteria are also more resistant to antibiotics because their outer membrane comprises a complex lipopolysaccharide (LPS) whose lipid portion acts as an endotoxin. Many gram-negative bacteria are also pathogenic e.g., Pseudomonas aeruginosa, Neisseria gonorrhoeae, Chlamydia trachomatis, and Yersinia pestis. Another 3 cause diseases in plants: Rathybacter, Leifsonia, and Clavibacter. Six gram-positive genera of bacteria are known to cause disease in humans: Streptococcus, Staphylococcus, Corynebacterium, Listeria, Bacillus and Clostridium. The following videos demonstrate the staining of Gram-positive and negative bacteria respectively.īoth gram-positive and gram-negative bacteria can be pathogenic (see list of pathogenic bacteria). Gram-positive and negative bacteria are chiefly differentiated by their cell wall structure Lipid content of the cell wall is low, whereas Murein content is 70-80% (higher). The cell wall is 100-120 Å thick single layered. Lipid content is 20-30% (high), Murein content is 10-20% (low). The cell wall is 70-120 Å (ångström) thick two layered. Low (acid-fast bacteria have lipids linked to peptidoglycan)

Retain crystal violet dye and stain dark violet or purple, they remain coloured blue or purple with gram stain when washed with absolute alcohol and water. Comparison chart Gram-negative Bacteria versus Gram-positive Bacteria comparison chartĬan be decolourized to accept counter stain (Safranin or Fuchsine) stain red or pink, they don't retain the Gram stain when washed with absolute alcohol and acetone.
